An online tool reveals the extent of gene-restructuring events in noncoding sequences. An interactive web portal developed by scientists at KAUST offers a platform for cancer researchers to ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

The human genome is just over 6 feet 8 inches long, which is 2 inches taller than the average NBA basketball player and in total, a lot of nucleotides! But what if the amount of sequence diversity ...

Plasmacytoid urothelial carcinoma: A clinicopathological study. This is an ASCO Meeting Abstract from the 2018 Genitourinary Cancers Symposium. This abstract does not include a full text component.

What eventually becomes a graduate student’s PhD thesis work is rarely the project they initially pursued. However, in rare cases like with recent PhD graduate Dr. April Lo from Dr. Alice Berger’s Lab ...

What we do know is that there are a lot of brain-specific alternative splicing events that consistently go wrong in neurological diseases. These include neurodevelopmental disorders, like autism ...

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays ...

Clinical Nomogram Using Novel Computed Tomography–Based Radiomics Predicts Survival in Patients With Non–Small-Cell Lung Cancer Treated With Stereotactic Body Radiation Therapy Colorectal cancer (CRC) ...

Take a genomic eukaryotic sequence, match it with a mature eukaryotic mRNA or a reverse-translated protein sequence, and you’ll discover the location of introns. These, of course, are spliced out ...

In cancers such as breast cancer where immunotherapy responses are seen in a small subset of patients, inducing T-cell responses against common mis-splicing events that generate neo-antigens holds ...