Abstract: Sequence alignment is a crucial tool in biological research. Alignment quality is typically assessed using scores, but these do not guarantee optimality. Estimating the optimal alignment ...

The reliability of multiple sequence alignment (MSA) results directly determines the credibility of the conclusions drawn from biological research. However, MSA is inherently an NP-hard problem, ...

US Secretary of State Marco Rubio has clarified that Washington’s renewed partnership with Pakistan will not come at the cost of its strong ties with India. Addressing media questions post-Operation ...

The one thing Rams safety Quentin Lake wanted to improve this season above all else was ball production. It's safe to say he's done that, leading the league with five pass breakups through three games ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. AlphaFold has ...

The phenomenon known as a planetary parade is back as astronomers and stargazers prepare for what could be a dazzling display in the solar system this week. The planetary parade — what appears to be a ...

I hope this email finds you well. My name is Xueqin Wang, and I am currently using your tool SpruceUp for processing multiple sequence alignment data. First, I want to express my appreciation for this ...

Current methods of assessing the similarity between proteins are based on protein sequence alignment. However, alignment is ineffective for intrinsically disordered regions (IDRs) given their rapid ...